Author

Jacob Appelbaum

University of WashingtonORCID 0000-0002-4362-7773Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam J JohnsoniD· 1 shared Anthony RongvauxiD· 1 shared Ardizon ValdeziD· 1 shared Axia SongiD· 1 shared Benjamin C. CurtisiD· 1 shared Cailyn H. SpurrelliD· 1 shared Christopher P SaxbyiD· 1 shared Derek L. StirewaltiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

Adam J JohnsonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 24, 2026

Somatic DDX41 mutations confer neomorphic splicing activity in the pathogenesis of myelodysplastic neoplasms

Rasika Venkataraman, Noemi Puccio, Tun‐Yun Hsueh…·Stanley Chun-Wei Lee

This study identifies somatic DDX41 mutations as gain-of-function alleles that drive aberrant splicing, particularly of SEPTIN7, contributing to MDS/AML pathogenesis.

DOI 10.64898/2026.09.23.753593

humanbulk RNA-seq

𝕏 PostBluesky

BioengineeringbioRxivPreprintDec 22, 2023

Rationally designed modular STAT-activating scaffolds enforce cell-intrinsic transcriptional programs augmenting the anti-tumor potency of CAR T cells

Christopher P Saxby, Taylor K Ishida, James M. Rosser…·Michael C. Jensen

This study designs and tests STAT-activating scaffolds to enhance CAR T cell anti-tumor potency, finding that LASI-3 improves function without lymphoproliferative side effects.

DOI 10.1101/2023.12.22.573170

humanbulk RNA-seq

𝕏 PostBluesky