MicrobiologybioRxiv
The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation
Luz Saavedra-Sanchez, Mary S Dickinson, Shruti S Apte…·Jörn Coers
This study identifies IpaH1.4 as a Shigella effector that degrades RNF213, preventing ubiquitylation of intracellular bacteria and evading host immunity.
11 citations