Author

Samantha Skavicus

Duke Medical CenterORCID 0009-0003-1380-8551Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Nicholas S. HeatoniD· 3 shared Carolyn B. CoyneiD· 1 shared Chia-Fang LeeiD· 1 shared David N. HareiD· 1 shared Debra L. SilveriD· 1 shared Emily N. Glidewell· 1 shared Federica MostiiD· 1 shared Jing LiuiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersImmunology

Nicholas S. HeatonORCID

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3 papers

Recent·Most cited

ImmunologymBioPeer-reviewedMay 5, 2026

Constitutive Interferon Epsilon Expression Shapes Antiviral Epithelial States in the Female Reproductive Tract and Intestine

Rebecca L. Casazza, Samantha Skavicus, David N. Hare…·Carolyn B. Coyne

This study identifies IFN{varepsilon} as a constitutively expressed IFN that maintains antiviral defenses in the female reproductive tract and intestine by sustaining specific epithelial states and type III IFN expression.

1 citation

mousehuman

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Developmental BiologyCell stem cellPeer-reviewedMar 19, 2026

Species-specific chromatin architecture and neurogenesis mediated by a human enhancer

Federica Mosti, Jing Liu, Katie Lam…·Debra L. Silver

The paper shows human-specific enhancer HAR1984 promotes neurogenesis by altering chromatin interactions and gene regulation in cortical organoids and mice.

6 citationstop 1%

humanmouse

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MicrobiologybioRxivSep 5, 2024

The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation

Luz Saavedra-Sanchez, Mary S Dickinson, Shruti S Apte…·Jörn Coers

This study identifies IpaH1.4 as a Shigella effector that degrades RNF213, preventing ubiquitylation of intracellular bacteria and evading host immunity.

11 citations

humanproteomics

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