MicrobiologybioRxivPreprint
The host protein cyclophilin A inhibits HIV-1 nuclear entry by decreasing capsid elasticity
Jun Hong, Akshay Deshpande, Yatish Thakare…·Christopher Aiken
This study shows that cyclophilin A inhibits HIV-1 nuclear entry in mutants by reducing capsid elasticity, which is reversed by suppressor mutations.
2 citations