Author
Florida State UniversityORCID 0000-0002-8663-2038Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Karen A. Kirby, William M. McFadden, Lin Wang…·Stefan G. Sarafianos
The paper characterizes structural, biophysical, and virological properties of HIV-1 capsid-targeting antivirals, showing improved potency and stability through chemical modifications of PF74.
Jun Hong, Akshay Deshpande, Yatish Thakare…·Christopher Aiken
This study shows that cyclophilin A inhibits HIV-1 nuclear entry in mutants by reducing capsid elasticity, which is reversed by suppressor mutations.
Lorenzo Briganti, Arun S. Annamalai, Stephanie M. Bester…·Mamuka Kvaratskhelia
This paper investigates how the M66I mutation in HIV-1 capsid protein confers resistance to lenacapavir by altering inhibitor binding and viral replication.
Szu‐Wei Huang, Lorenzo Briganti, Arun S. Annamalai…·Mamuka Kvaratskhelia
This study identifies the mechanism by which lenacapavir inhibits HIV-1 maturation by altering capsid protein assembly.