Author

Jiyuan Piao

University of AlbertaORCID 0000-0002-4435-7285Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Evangelos D. MichelakisiD· 2 shared Gopinath SutendraiD· 2 shared Yongneng ZhangiD· 2 shared Yongsheng LiuiD· 2 shared Alois HaromyiD· 1 shared Dawn E. BowlesiD· 1 shared Jacob R. HambrookiD· 1 shared John R. UssheriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMolecular Biology

Evangelos D. MichelakisORCID

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2 papers

Recent·Most cited

A critical contribution of cardiac myofibroblasts in right ventricular failure and the role of UCP2 SNPs in the predisposition to RV decompensation in pulmonary arterial hypertension

Yongneng Zhang, Sébastien Bonnet, Steeve Provencher, Jiyuan Piao, Alois Haromy, Yongsheng Liu, Yuan-Yuan Zhao, Sandra Breuils‐Bonnet, Sarah-Eve S Lemay, Dawn E. Bowles, M. Mendiola, Gopinath Sutendra, Evangelos D. Michelakis

The paper investigates the role of cardiac myofibroblasts and UCP2 SNPs in right ventricular failure in pulmonary arterial hypertension, finding increased cMFB and reduced UCP2 associated with decompensation.

Circulation · Mar 9, 2026Peer-reviewedMolecular Biology

An inducer of snail hibernation causes quiescence and hibernation-like cardioprotection, through metabolic rewiring and autophagy, in mice hearts

Jiyuan Piao, Yongneng Zhang, Yuanyuan Zhao, Patrick C. Hanington, Jacob R. Hambrook, Yongsheng Liu, John R. Ussher, Seyed Amirhossein Tabatabaei Dakhili, Gopinath Sutendra, Evangelos D. Michelakis

This study identifies a hibernation-inducing factor from snails, SNAP, which induces quiescence and cardioprotection in mice hearts through metabolic rewiring and autophagy during ischemia-reperfusion injury.

bioRxiv · Jan 9, 2026 · PreprintCell Biology