A critical contribution of cardiac myofibroblasts in right ventricular failure and the role of UCP2 SNPs in the predisposition to RV decompensation in pulmonary arterial hypertension
Yongneng Zhang, Sébastien Bonnet, Steeve Provencher, Jiyuan Piao, Alois Haromy, Yongsheng Liu, Yuan-Yuan Zhao, Sandra Breuils‐Bonnet, Sarah-Eve S Lemay, Dawn E. Bowles, M. Mendiola, Gopinath Sutendra, Evangelos D. Michelakis
The paper investigates the role of cardiac myofibroblasts and UCP2 SNPs in right ventricular failure in pulmonary arterial hypertension, finding increased cMFB and reduced UCP2 associated with decompensation.
Circulation · Mar 9, 2026Peer-reviewedMolecular Biology