Kaisa Thorell

Introducing a gastric microbial model community

This study develops a gastric microbial model community to investigate H. pylori interactions with other microbes and their impact on pathogenesis.

Global diversity of integrating conjugative elements (ICEs) in Helicobacter pylori and their influence on genome architecture

The paper analyzes ICE content and variability in 1011 H. pylori strains, showing their prevalence, gene erosion, and role in shaping genome architecture through horizontal transfer and recombination.

Functional and intricate interaction network connecting Helicobacter pylori Cag Type 4 Secretion System surface proteins with outer membrane proteins HopQ and HopZ

This study identifies and characterizes a network of interactions between Helicobacter pylori outer membrane proteins and CagT4SS surface proteins, revealing their functional importance in transport processes.

Building pangenome graphs

This paper introduces PGGB, a pipeline for building pangenome graphs that includes all variation without bias, enabling variation detection, conservation measurement, recombination event detection, and phylogenetic inference.

Epstein-Barr virus long non-coding RNA RPMS1 full-length spliceome in transformed epithelial tissue

The paper characterizes the full-length spliceome of Epstein-Barr virus RPMS1 using long-read and short-read sequencing, identifying novel exons and splice variants.

Taxonomic identification from metagenomic and metabarcoding data using any genetic marker

The paper updates Metaxa2 to support taxonomic classification using any genetic marker for metagenomic and metabarcoding data.

Rapid evolution of distinct Helicobacter pylori subpopulations in the Americas

This study analyzes H. pylori genome sequences from the Americas to show rapid evolution and genetic exchange leading to distinct subpopulations linked to human demographics and transmission ecology.