J. C. Noble

The paper shows that disrupting epigenetic barriers in olfactory placode-derived cells can induce stem cell-like characteristics through genetic perturbations.

This paper introduces a synthetic thermostable RNase inhibitor that improves single-cell RNA-seq library quality, reproducibility, and workflow flexibility compared to protein-based inhibitors.

Voltage-Seq enables targeted single-cell transcriptome profiling of postsynaptic neurons based on specific voltage response types using all-optical voltage imaging and a connectome database.

Voltage-Seq enables targeted single-cell RNA-sequencing of neurons based on their postsynaptic response types using all-optical voltage imaging and a connectome-guided analysis tool.

This study uses allele-resolved single-cell multi-omics to reveal the dynamics and transcriptional kinetics of X-chromosome upregulation in mouse development.