Antonio Lentini

The paper investigates transcriptional responses to autosomal aneuploidies and finds evidence for global dosage compensation across aneuploid chromosomes.

This paper introduces a synthetic thermostable RNase inhibitor that improves single-cell RNA-seq library quality, reproducibility, and workflow flexibility compared to protein-based inhibitors.

The paper examines dosage compensation mechanisms on the avian Z chromosome in female, male, and intersex chickens, revealing transcriptional and translational strategies similar to mammalian X-chromosome compensation.

The paper identifies six glutamatergic neuron types in the LHA-LHb pathway, showing that Esr1+ neurons induce aversion and are involved in stress sensitivity in female mice.

This study uses allele-resolved single-cell multi-omics to reveal the dynamics and transcriptional kinetics of X-chromosome upregulation in mouse development.

Smart3-ATAC enables joint analysis of mRNA and chromatin accessibility in single cells with higher yield than existing droplet multiome methods.

This study identifies and corrects a major source of error in DIP-seq data, revealing new biological insights and proposing methodological improvements.