Daniela Calvigioni

This study identifies S100A6 as a signaling molecule released by astrocytes that modulates neuronal development by inhibiting CaCyBp-mediated signaling, affecting proteostasis and neuritogenesis.

The paper investigates VMH-coll neurons' role in defensive behavior plasticity, finding they modulate freezing and escape behaviors through inhibitory mechanisms and neuropeptide modulation.

The paper identifies a striosomal ACB projection to the Esr1+ LHA-LHb pathway that drives compulsive seeking behaviors through aversive signaling.

Voltage-Seq enables targeted single-cell transcriptome profiling of postsynaptic neurons based on specific voltage response types using all-optical voltage imaging and a connectome database.

This study identifies a selective subthalamostriatal projection to parvalbumin-expressing interneurons in the striatum, showing higher connectivity and excitatory responses compared to other cell types.

The paper identifies six glutamatergic neuron types in the LHA-LHb pathway, showing that Esr1+ neurons induce aversion and are involved in stress sensitivity in female mice.

The paper shows that all three major striatal output pathways represent action space and value similarly during motor and decision tasks.

The paper shows that neurogliaform cells in mouse and human exhibit similar activity-dependent changes in intrinsic excitability, suggesting conserved circuit mechanisms across species.

The paper maps the molecular and spatial organization of striatal projection neurons, identifying new subtypes and spatial domains in both mice and non-human primates.