Pierre Llorach

This paper introduces engineered mouse models to study the effects of psychedelic drugs by examining HTR2A receptor expression and function.

The paper uses cryo-EM to analyze endogenous mGluR2-containing receptor assemblies in mouse brain, revealing distinct structural states and complexes not previously observed in recombinant systems.

This study identifies the somatosensory cortex as a sex-specific regulator of high-fat diet intake through brain-wide activity mapping and chemogenetic manipulation in mice.

This study investigates the differential roles of D1- and D2-MSNs in regulating hedonic feeding in male and female mice using optogenetics, chemogenetics, and fiber photometry.

This paper investigates how 5-HT2C receptors in the nucleus accumbens modulate MDMA's rewarding effects and prosocial behaviors through interactions with serotonin and dopamine release.

The paper identifies opioid receptor-expressing neurons in the central amygdala as mediators of ketamine's behavioral effects in mice, showing they are not direct targets of ketamine.