Author

Timothy J. Nice

Oregon Health & Science UniversityORCID 0000-0002-4471-7666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

David A. ConstantiD· 2 shared Gargi MishraiD· 2 shared Ram SavaniD· 2 shared Adam Lacy‐HulbertiD· 1 shared Adelle P. McFarlandiD· 1 shared Alec M. GriffithiD· 1 shared Emily A. HemanniD· 1 shared Hayley Waterman· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

David A. ConstantORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 10, 2026

Lineage-specific chromatin poising enforced by ETS-IRF composite elements determines the divergent interferon responses of plasmacytoid dendritic cells and epithelial cells

Gargi Mishra, Snehal Ozarkar, Yo Okamura…·Ram Savan

This paper identifies lineage-specific chromatin accessibility differences at IFN gene loci in pDCs and epithelial cells, revealing ETS-IRF composite elements as key regulators of divergent interferon responses.

1 citation

humanATAC-seq

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ImmunologybioRxivPreprintAug 25, 2025

Plasmacytoid dendritic cells in the intestine preferentially produce interferon lambda at homeostasis contributing to tonic localized innate immune responses

David A. Constant, Jacob A. Van Winkle, Philip A Norwood…·Timothy J. Nice

This study identifies intestinal plasmacytoid dendritic cells (pDC) as a major source of homeostatic IFN-λ and shows TGF-β regulates their IFN production.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky