Arp2/3 complex-dependent actin regulation protects the survival of tissue-resident mast cells
Lukas Kaltenbach, Michael Mihlan, Svenja Ulferts, Mathias Müsken, Katharina M. Glaser, Gerhard Mittler, Magda Babina, Metello Innocenti, Robert Grosse, Theresia E. B. Stradal, Tim Lämmermann
This study identifies the Arp2/3 complex as critical for maintaining mast cell survival and tissue residency through actin-dependent mechano-protection.
bioRxiv · Feb 23, 2024 · PreprintImmunology