The paper systematically identifies and characterizes cancer-emergent oncRNAs across 32 tumor types, showing they act as blood-accessible molecular barcodes for cancer identity and prognosis.

Cell Reports Medicine · Jan 23, 2026Peer-reviewedCancer Biology

The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ

Daniela Nachmanson, Adam Officer, Hidetoshi Mori, Jonathan Gordon, Mark Francis Evans, Joseph Steward, Huazhen Yao, Thomas J. O’Keefe, Farnaz Hasteh, Gary Stephen Stein, Kristen Jepsen, Donald L. Weaver, Gillian L. Hirst, Brian L. Sprague, Laura J. Esserman, , Olivier Harismendy

The paper creates a breast pre-cancer atlas by analyzing multiple micro-dissected regions from DCIS cases, revealing molecular and micro-environmental diversity and immune states associated with progression risk.

npj Breast Cancer · Jan 13, 2022Peer-reviewedGenomics

Mutational profiling of micro-dissected pre-malignant lesions from archived specimens

Daniela Nachmanson, Joseph Steward, Huazhen Yao, Adam Officer, Eliza Jeong, Thomas J. O’Keefe, Farnaz Hasteh, Kristen Jepsen, Gillian L. Hirst, Laura J. Esserman, Alexander D. Borowsky, Olivier Harismendy

This paper develops a method to improve mutational profiling of pre-malignant lesions using degraded FFPE DNA, achieving better coverage and variant calling accuracy.

BMC Medical Genomics · Nov 18, 2020Peer-reviewedGenomics