Benjamin Hänisch

This study examines the molecular affinities of 18 antidepressants, identifies three clusters, and links receptor affinity to efficacy and brain distribution.

The paper develops anatomical distribution profiles of psychedelic and anaesthetic drugs to understand their rapid antidepressant effects by combining pharmacodynamic data with receptor density maps.

The paper systematically identifies and characterizes cancer-emergent oncRNAs across 32 tumor types, showing they act as blood-accessible molecular barcodes for cancer identity and prognosis.

The paper identifies ZZEF1 as a tRNA-specific transcription factor that suppresses breast cancer metastasis by regulating tRNA-LysUUU expression and affecting codon-specific translation.

The paper examines how neurotransmitter receptor/transporter molecule (NTRM) co-expression patterns in the brain share organizational traits with brain structure and function.

The paper identifies RBMS1 as a suppressor of colon cancer metastasis by stabilizing its mRNA targets, showing its clinical relevance in patient survival.

This study identifies a DEGS1 mutation causing sphingolipid metabolism defects, leading to neurological disorders and suggests dietary intervention as a potential treatment.