Author

Hidetoshi Mori

University of California, DavisORCID 0000-0002-5950-281XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alexander D. BorowskyiD· 3 shared Joshua C. SnyderiD· 2 shared Adam Officer· 1 shared Alejandra V. PatinoiD· 1 shared Allison J. Introne· 1 shared Brian L. SpragueiD· 1 shared Bruce Rogers· 1 shared Daniela NachmansoniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

Alexander D. BorowskyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

P95-HER2 promotes metastatic progression by biasing MRTFA dependent signaling

Joseph D. Fernandes, Erin R. Bresnahan, Hillary Zawada, Joshua D. Ginzel, Herbert Kim Lyerly, Bruce Rogers, Shyam M. Kavuri, Allison J. Introne, Melanie R Sadecki, Hidetoshi Mori, Glenn Doherty, Alexander D. Borowsky, Kevin Flores, Jose Javier Bravo‐Cordero, Joshua C. Snyder

This study shows that the p95 isoform of HER2 promotes metastasis by biasing MRTFA-dependent signaling through specific tyrosine phosphorylation.

bioRxiv · Jul 23, 2026 · PreprintCell Biology

Adaptive selection of p53 mutation metaplastic phenotypes in estrogen-independent progression of ER+ tumors: A mechanism for acquired resistance to hormonal therapy.

Hyeongsun Moon, Hidetoshi Mori, Jane Chen, Alejandra V. Patino, Zsófia Pénzváltó, Kavya Ramamurthy, Jaeyong Choi, John D. McPherson, Joshua C. Snyder, Robert D. Cardiff, Alexander D. Borowsky

This study shows that ER+ breast cancers can develop resistance to hormonal therapy through clonal selection of metaplastic p53-mutated basal cells in Stat1-/- mice.

bioRxiv · Feb 2, 2025 · PreprintCancer Biology

The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ

Daniela Nachmanson, Adam Officer, Hidetoshi Mori, Jonathan Gordon, Mark Francis Evans, Joseph Steward, Huazhen Yao, Thomas J. O’Keefe, Farnaz Hasteh, Gary Stephen Stein, Kristen Jepsen, Donald L. Weaver, Gillian L. Hirst, Brian L. Sprague, Laura J. Esserman, , Olivier Harismendy

The paper creates a breast pre-cancer atlas by analyzing multiple micro-dissected regions from DCIS cases, revealing molecular and micro-environmental diversity and immune states associated with progression risk.

npj Breast Cancer · Jan 13, 2022Peer-reviewedGenomics