Author

Linda Shearwin‐Whyatt

The University of AdelaideORCID 0000-0002-4504-6534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 2 Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:plant (other)· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Frank GrützneriD· 4 shared Rachel van der PloegiD· 2 shared Zhipeng QuiD· 2 shared Alexander Stuart· 1 shared Andrew Thomas MajoriD· 1 shared Craig A. SmithiD· 1 shared Daniel P. McDougaliD· 1 shared David L. AdelsoniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersEvolutionary Biology

Frank GrütznerORCID

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4 papers

Recent·Most cited

Monotremes provide novel insights into evolution of the DMRT gene family in vertebrates

Rachel van der Ploeg, Linda Shearwin‐Whyatt, Frank Grützner

The paper analyzes DMRT gene family evolution in monotremes and other vertebrates, identifying conserved genes and unique features in monotremes.

bioRxiv · Jul 20, 2026 · PreprintGenetics

AMHY and sex determination in egg-laying mammals

Linda Shearwin‐Whyatt, Jane C. Fenelon, Hongshi Yu, Andrew Thomas Major, Zhipeng Qu, Yang Zhou, Keith Edward Shearwin, James D. Galbraith, Alexander Stuart, David L. Adelson, Guojie Zhang, Michael J. Pyne, Stephen Douglas Johnston, Craig A. Smith, Marilyn B. Renfree, Frank Grützner

This study identifies AMHY as the primary male sex determination gene in monotremes by analyzing its expression and function during sexual differentiation.

Genome biology · May 27, 2025Peer-reviewedEvolutionary Biology

Structural evolution of the estrogen receptor regulatory domain

Daniel P. McDougal, Jordan L. Pederick, Linda Shearwin‐Whyatt, Frank Grützner, John B. Bruning

This study analyzes the structural evolution of estrogen receptor regulatory domains, revealing conserved network structures and their implications for breast cancer and reproductive disorders.

bioRxiv · Dec 18, 2024 · PreprintBiochemistry

Pseudogenisation of NK3 Homeobox 2 (Nkx3.2) in Monotremes Provides Insight into Unique Gastric Anatomy and Physiology

Jackson Dann, Zhipeng Qu, Linda Shearwin‐Whyatt, Rachel van der Ploeg, Frank Grützner

The paper identifies pseudogenisation of Nkx3.2 in monotremes and links it to unique gastric anatomy and physiology, suggesting gene loss influences phenotypic evolution.

Open Biology · Jul 1, 2024Peer-reviewedEvolutionary Biology