Author

Jason W. Sidabras

Medical College of WisconsinORCID 0000-0002-4537-7501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Assay:electronic health records· 2 Assay:imaging· 2 Research Focus:protein folding & dynamics· 2 Research Focus:synaptic & neural circuits· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1

Frequent Co-Authors

Michael T. LerchiD· 3 shared Richard R. Mett· 3 shared Alexander M. GarcesiD· 2 shared Anand Anilkumar· 2 shared Candice S. KlugiD· 2 shared Kyle A. JohnsoniD· 2 shared Alexander M Garces· 1 shared Andrew S. NenckaiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersBiophysics

Michael T. LerchORCID

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Author profile →

7 papers

Recent·Most cited

Ultra-precision 3D Printed Sample Tubes of Complex Cross Section for Enhanced Electron Paramagnetic Resonance Sensitivity of AqueousSamples

Anand Anilkumar, Joseph T Wherley, Alexander M Garces, Michael Lerch, Candice Klug, Jason W. Sidabras

This paper develops 3D printed EPR sample tubes with complex cross-sections to enhance signal sensitivity in aqueous samples, validated through simulations and experiments.

bioRxiv · Nov 2, 2026 · PreprintBiophysics

Single Channel Strongly-Coupled Geometry Surface Coil for Small Mammal Whole Brain fMRI

Kyle Johnson, Hanbing Lu, Jason W. Sidabras

This paper introduces a single-channel strongly-coupled geometry surface coil for rodent whole-brain fMRI, showing improved depth sensitivity and consistent signal-to-noise ratio across loading conditions.

bioRxiv · Aug 7, 2026 · PreprintBiophysics

A High-Sensitivity Stopped-Flow EPR System to Monitor Millisecond Conformational Kinetics in Spin-Labeled Proteins

Alexander M. Garces, Richard R. Mett, Candice S. Klug, Jason W. Sidabras, Michael T. Lerch

The paper develops a high-sensitivity stopped-flow EPR system for studying millisecond protein conformational dynamics, demonstrating its use on T4 lysozyme and β2 adrenergic receptor.

Protein Science · Jul 16, 2025Peer-reviewedBiophysics

Improved EPR sensitivity for aqueous biological samples using low-volume multi-channel cells and dielectric resonators

Richard R. Mett, Alexander M. Garces, Anand Anilkumar, Joseph T. Wehrley, Michael T. Lerch, Candice S. Klug, Jason W. Sidabras

This paper improves EPR sensitivity for small aqueous biological samples using optimized dielectric resonators and multi-channel cells.

bioRxiv · Jun 3, 2025 · PreprintBiophysics

An Order of Magnitude Signal-to-Noise Improvement of Magnetic Resonance Spectra using a Segmented-Overlap Fourier-Filtering and Averaging (SOFFA) Approach.

Jason W. Sidabras

The paper introduces SOFFA, a method improving magnetic resonance spectra signal-to-noise ratio by 5.6-10.3 times across different experiments without increasing acquisition time.

bioRxiv · Apr 21, 2025 · PreprintBiophysics

A pressure-jump EPR system to monitor millisecond conformational exchange rates of spin-labeled proteins

Julian D. Grosskopf, Jason W. Sidabras, Christian Altenbach, Jim R. Anderson, Richard R. Mett, Robert A. Strangeway, James S. Hyde, Wayne L. Hubbell, Michael T. Lerch

The paper introduces a pressure-jump EPR system to measure millisecond conformational exchange rates in spin-labeled proteins and demonstrates its application to T4 lysozyme.

Protein Science · Nov 20, 2024Peer-reviewedBiophysics

Asymmetric spin echo multi-echo echo planar imaging (ASEME-EPI) sequence for pre-clinical high-field fMRI

Kyle A. Johnson, Christopher P. Pawela, Andrew S. Nencka, Jason W. Sidabras

This paper introduces ASEME-EPI, a new fMRI sequence combining GRE and SE to improve BOLD contrast-to-noise ratio and specificity in high-field preclinical imaging.

bioRxiv · Oct 12, 2024 · PreprintBiophysics