Author

Mesude Bicak

Icahn School of Medicine at Mount SinaiORCID 0000-0002-4546-9801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jean‐Vianney Haure‐MirandeiD· 2 shared Michelle E. EhrlichiD· 2 shared Sam GandyiD· 2 shared Aisha Al-subaie· 1 shared Alena Otero‐Pagan· 1 shared Benjamin P. Readhead· 1 shared Benjamin Scott GlicksbergiD· 1 shared Carrolee Barlow· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Jean‐Vianney Haure‐MirandeORCID

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2 papers

Recent·Most cited

miR155 triplicated in Down syndrome regulates hippocampal GABAergic neurogenesis in Alzheimer's disease

Xiaodong Zhu, Jean‐Vianney Haure‐Mirande, Mesude Bicak, Pengfei Dong, Ilya Kruglikov, Aisha Al-subaie, Valentina Fossati, Scott Noggle, Sam Gandy, Michelle E. Ehrlich

The paper investigates miR155's role in hippocampal GABAergic neurogenesis in Alzheimer's disease, finding it regulates NSC dynamics and interneuron development with opposing effects compared to microglial miR155.

bioRxiv · Sep 28, 2025 · PreprintNeuroscience

Orally active mGluR2/3 metabotropic antagonist pro-drug mimics the beneficial effects of physical exercise on neurogenesis, behavior, and exercise-related molecular pathways in an Alzheimer's disease mouse model

Georgina Perez-Garcia, Mesude Bicak, Jacqueline L. Buros, Jean‐Vianney Haure‐Mirande, Gissel M. Perez, Alena Otero‐Pagan, Miguel A. Gama Sosa, Rita De Gasperi, Mary C. Sano, Fred H. Gage, Carrolee Barlow, Joel T. Dudley, Benjamin Scott Glicksberg, Yanzhuang Wang, Benjamin P. Readhead, , Sam Gandy

This study shows that BCI-838, a mGluR2/3 antagonist, mimics exercise's benefits on neurogenesis, behavior, and molecular pathways in an Alzheimer's mouse model.

bioRxiv · Jan 31, 2022 · PreprintNeuroscience