Author

Alexander MacKenzie

University of MichiganORCID 0000-0003-3963-0643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Abigail J. TomlinsoniD· 1 shared Alan C. RuppiD· 1 shared Alexander Manta· 1 shared Alison H. AffinatiiD· 1 shared Andreas HentscheliD· 1 shared Andreas RoosiD· 1 shared Aymeric Ravel‐Chapuis· 1 shared Cadence A. TrueiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Abigail J. TomlinsonORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 4, 2025

Acute AMPK activation does not adequately stimulate insulin signaling in skeletal muscle models of Myotonic Dystrophy Type 1

Ofosu Adjei-Afriyie, Sally Spendiff, Ricardo Carmona-Martinez…·Hanns Lochmüller

This study shows that acute AMPK activation fails to improve insulin signaling in DM1 mouse and human models, indicating impaired insulin resistance mechanisms.

DOI 10.1101/2025.11.04.686135

mousehuman

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 10, 2021

Leptin-mediated suppression of food intake by conserved Glp1r-expressing neurons prevents obesity

Alan C. Rupp, Abigail J. Tomlinson, Alison H. Affinati…·Martin Grosvenor Myers

The paper identifies a conserved population of GABAergic Glp1r-expressing LepRb neurons that mediate leptin's suppression of food intake and prevention of obesity.

5 citations

mousescRNA-seq

𝕏 PostBluesky