Elisa Balmas

This paper introduces GERALT, a genetic circuit that enables TGFβ-independent hiPSC renewal and inducible lineage programming, improving differentiation efficiency and reducing medium complexity.

CALIPERS enables cell cycle-aware live imaging by integrating a modified FUCCI variant, analysis software, and reporter lines for phenotyping and regeneration studies.

The paper introduces CIRI, a CRISPR-based platform for programmable cell fate conversion in hiPSCs, using single-cell genomics to identify regulatory factors for myogenic differentiation.

The paper shows that CTCF and GATA4 have opposing roles in chromatin remodeling during cardiomyogenesis, with CTCF inhibiting and GATA4 promoting topological changes.

The paper uses O-MAP to study a cardiac-specific RNA factory around TTN RNA, revealing its chromatin interactions, RNA composition, and role of RBM20 in gene regulation.