Elisa Hahn

Opposing CTCF and GATA4 activities set the pace of chromatin topology remodeling during cardiomyogenesis

The paper shows that CTCF and GATA4 have opposing roles in chromatin remodeling during cardiomyogenesis, with CTCF inhibiting and GATA4 promoting topological changes.

Metabolic control of germ layer proportions through regulation of Nodal and Wnt signalling

The paper shows that glycolytic activity regulates germ layer proportions by modulating Nodal and Wnt signalling in mouse gastrulation.

Collective fate decisions and cell rearrangements underlie gastruloid symmetry breaking

The paper shows that collective cell fate decisions and mechanical differences drive symmetry breaking in gastruloids through a mechanochemical mechanism.

E3-specific degrader discovery by dynamic tracing of substrate receptor abundance

This paper develops a scalable method to identify E3-specific degraders by tracing substrate receptor abundance changes induced by pharmacological auto-degradation.