NeurosciencebioRxivPreprint
Highly specific σ2R/TMEM97 ligand alleviates neuropathic pain and inhibits the integrated stress response
Muhammad Saad Yousuf, James J. Sahn, Hongfen Yang…·Theodore John Price
This paper identifies FEM-1689 as a σ2R/TMEM97 ligand that alleviates neuropathic pain by inhibiting the integrated stress response in mice and human sensory neurons.