Author

Eric M. Mucker

United States Army Medical Research Institute of Infectious DiseasesORCID 0000-0002-4656-5379Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Aura R. GarrisoniD· 2 shared Joseph W. GoldeniD· 2 shared Alec W. FreyniD· 1 shared Alicia MasiD· 1 shared Alı́ AlejoiD· 1 shared Andrea Carfı́iD· 1 shared April M. BabkaiD· 1 shared Ashley E. PiperiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

Aura R. GarrisonORCID

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4 papers

Recent·Most cited

Stability and characterization of infectious monkeypox virus extracellular virions in vitro2and vivo; implications for transmission, pathogenesis and treatment

K. Ostrowski, C. Davis, Sandra L. Bixler, Aura R. Garrison, Joseph W. Golden, Ashley E. Piper, Jeffrey W. Koehler, S. K. Ricks, Janice A. Williams, Eric M. Mucker

This study characterizes the stability and infectious properties of monkeypox and vaccinia virus extracellular virions in vitro and in vivo, highlighting strain- and cell line-dependent variations in their behavior.

bioRxiv · Mar 12, 2025 · PreprintMicrobiology

In vitro and in vivo Antiviral Activity of the Acyclic Nucleoside Phosphonate Prodrug LAVR-289 against Poxvirus and African Swine Fever Virus Replication

Elie Marcheteau, Estelle Mosca, Gaelle Frénois-Veyrat, Sandrine Kappler‐Gratias, Laetitia Boutin, Sokunthea Top, Thomas Mathieu, Cyril Colas, Patrick Favetta, Tony Garnier, Peggy Barbe, Mathilde Keck, Daniel Gillet, Alicia Mas, Alı́ Alejo, , Franck Gallardo

This study evaluates LAVR-289, a nucleoside analogue, showing antiviral activity against poxviruses and ASFV in vitro and in vivo with no toxicity.

bioRxiv · Feb 20, 2025 · PreprintMicrobiology

Mpox mRNA-1769 Vaccine Inhibits Orthopoxvirus Replication at Intranasal, Intrarectal, and Cutaneous Sites of Inoculation

Catherine A. Cotter, Maxinne A. Ignacio, Jeffrey L. Americo, Patricia L. Earl, Eric M. Mucker, Tiffany R. Frey, Andrea Carfı́, Jay W. Hooper, Alec W. Freyn, Bernard Moss

The paper shows that an mRNA vaccine against mpox reduces virus replication at multiple inoculation sites and provides protection with a single dose, supported by antibody-mediated immunity.

npj Vaccines · Dec 24, 2024Peer-reviewedMicrobiology

Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease

Joseph W. Golden, Curtis R. Cline, Xiankun Zeng, Aura R. Garrison, Brian D. Carey, Eric M. Mucker, Lauren E. White, Joshua D. Shamblin, Rebecca L. Brocato, Jun Liu, April M. Babka, Hypaitia B. Rauch, Jeffrey M. Smith, Bradley S. Hollidge, Collin Fitzpatrick, , Jay W. Hooper

This study shows that human ACE2 transgenic mice infected with SARS-CoV-2 develop severe respiratory disease, with males more susceptible than females.

bioRxiv · Jul 9, 2020Microbiology