GFI1 as a novel regulator of γδ T cell development and the IL-17/IFNγ lineage commitment
Jennifer Fraszczak, David Obwegs, Kaifee Arman, Tanja Muralt, Bavanitha Thurairajah, Ève Mallet Gauthier, Irah L. King, Heather J. Melichar, Sagar, Tarik Möröy
This paper identifies GFI1 as a regulator of γδ T cell development, showing it restricts IL-17-producing cells and promotes other γδ T cell subsets through repression of MAF.
Frontiers in Immunology · Aug 5, 2026Peer-reviewedImmunology