Irah L. King

This study shows that differences in gut microbiota between two mouse vendors affect susceptibility to C. difficile infection, and cohousing can transfer resistance.

This paper identifies GFI1 as a regulator of γδ T cell development, showing it restricts IL-17-producing cells and promotes other γδ T cell subsets through repression of MAF.

The paper identifies a microbiota-dependent type 3 immune response in mice during weaning that involves γδ T cells, which limit C. difficile growth and maintain intestinal barrier integrity.

This study shows that the LRRK2 G2019S mutation enhances neutrophil effector functions and drives intestinal inflammation in a mouse model of infectious colitis.

This study shows that gut microbiota from fibromyalgia patients causes pain in mice, and transferring healthy microbiota alleviates symptoms in humans.

This study shows that type 1 immunity, via IFNγ signaling, protects intestinal tissue from damage during helminth infection without reducing parasite burden.

This study identifies genetic risk factors for chronic post-surgical pain through GWAS across five surgery types, finding immune-related genes contribute significantly to heritability.