David Obwegs

This paper identifies GFI1 as a regulator of γδ T cell development, showing it restricts IL-17-producing cells and promotes other γδ T cell subsets through repression of MAF.

This study shows that streptococcal meningoencephalitis alters monocyte and macrophage dynamics in the dura by shifting their origin from skull bone marrow to peripheral sources and increasing MDP-Mo-derived cells.

This study maps the postnatal differentiation trajectories of dendritic epidermal T cells and Langerhans cells in mice, showing they develop independently of each other and microbial colonization.

The paper investigates KC plasticity in mycobacterial infections, finding that KClow cells derived from bona fide KCs exhibit unique antimycobacterial activity and adaptability.

This study shows the PIDDosome restricts cardiomyocyte polyploidization during postnatal heart development through p21/Cdkn1a, independent of p53.

This study shows colibactin-producing E. coli promote GEAC carcinogenesis by increasing proliferation, DNA damage, and cancer pathways, while also inducing autophagy and differentiation.