Bavanitha Thurairajah

The Microbiota Dictates Vendor-Derived Differences in a Murine Clostridioides difficile Infection Model

This study shows that differences in gut microbiota between two mouse vendors affect susceptibility to C. difficile infection, and cohousing can transfer resistance.

GFI1 as a novel regulator of γδ T cell development and the IL-17/IFNγ lineage commitment

This paper identifies GFI1 as a regulator of γδ T cell development, showing it restricts IL-17-producing cells and promotes other γδ T cell subsets through repression of MAF.

Early life γδT cell activation enforces intestinal barrier integrity during intergenerational C. difficile colonization

The paper identifies a microbiota-dependent type 3 immune response in mice during weaning that involves γδ T cells, which limit C. difficile growth and maintain intestinal barrier integrity.

Gut microbiota promotes pain in fibromyalgia

This study shows that gut microbiota from fibromyalgia patients causes pain in mice, and transferring healthy microbiota alleviates symptoms in humans.