Rasmus Rydbirk

Single cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss

This study examines transcriptional changes in human adipose tissue during weight loss from lifestyle and bariatric surgery, showing significant remodeling and reduced inflammation.

Single-cell profiling of cortical tubers in tuberous sclerosis complex shows molecular structure preservation and massive reorganization of metabolism

The paper uses single-nucleus RNA sequencing to analyze cortical tubers in TSC, finding preserved neuronal subtypes and metabolic reorganization in neurons.

Selective vulnerability of supragranular layer neurons in schizophrenia

The paper identifies selective vulnerability of supragranular layer neurons in schizophrenia through single nucleus RNA sequencing and histological analysis.

Case-control analysis of single-cell RNA-seq studies

Cacoa packages statistical tests, exploration and plots for comparing groups of scRNA-seq samples, aimed at inter-individual variability, small cohorts and high-dimensional data.