Christopher A. P. Batho

This study identifies prenylation as a regulator of cardiomyocyte proliferation through multiple targets, suggesting its potential for cardiac regeneration.

This paper shows that blocking glucocorticoid receptors enhances the effectiveness of growth factors in promoting cardiac regeneration by restoring MAPK/ERK signaling in cardiomyocytes.

This study shows that maturing human cardiac organoids enhances disease modeling and drug discovery by mimicking in vivo development and enabling therapeutic testing for DSP cardiomyopathy.

The paper describes HiBit technology for quantifying mRNA translation kinetics in vitro and in cellulo, showing its adaptability and utility for mRNA-based therapeutics.

This study shows that modified mRNA encoding Myc and Cyclin T1 can induce cardiomyocyte proliferation and improve cardiac function after myocardial injury in mice.