Catherine H. Wilson

This paper shows that blocking glucocorticoid receptors enhances the effectiveness of growth factors in promoting cardiac regeneration by restoring MAPK/ERK signaling in cardiomyocytes.

The paper describes HiBit technology for quantifying mRNA translation kinetics in vitro and in cellulo, showing its adaptability and utility for mRNA-based therapeutics.

This study identifies Angiotensin II as a pro-nociceptive mediator in IBD by showing increased Agt expression and AT1 receptor activation in colonic neurons.

This study shows that modified mRNA encoding Myc and Cyclin T1 can induce cardiomyocyte proliferation and improve cardiac function after myocardial injury in mice.

The paper constructs polygenic indexes for 47 phenotypes across 11 datasets and provides a tool to correct errors-in-variables bias when using PGIs as proxies for the additive SNP factor.

This study identifies two genetic loci, GDF5 and COL27A1, associated with knee pain through a genome-wide association analysis in the UK Biobank and replication in other cohorts.

This study shows common genetic variants significantly contribute to migraine family clustering, with higher burden in familial cases compared to population-based cases.

This study conducts a GWAS on depression phenotypes in UK Biobank, identifying genetic variants enriched in excitatory synaptic pathways.

This study investigates genetic mechanisms underlying sex bias in ADHD prevalence using genome-wide data and finds no mean polygenic burden difference across sexes but increased risk in female siblings and comorbid conditions.

This study replicates and extends findings of CADM2 and MSRA gene associations with personality traits using data from 23andMe.