Engineering nanoparticles that target fibroblast activation protein in cardiac fibrosis
Chima V. Maduka, Gabriel J. Rodriguez‐Rivera, Manuela Garay‐Sarmiento…·Jason A. Burdick
This paper develops anti-FAP antibody-modified nanoparticles that target cardiac fibrosis in a rat model, reducing talabostat dose by 400,000-fold and reversing fibrosis and dysfunction.