Systems BiologybioRxivPreprint
The mechanism of artemisinin resistance of Plasmodium falciparum malaria parasites originates in their initial transcriptional response.
Lei Zhu, Rob W. van der Pluijm, Michal Kucharski…·Zbynek Bozdech
The paper identifies a transcriptional profile in artemisinin-resistant Plasmodium falciparum that originates from initial drug responses and involves proteotoxic stress and REDOX metabolism.
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