Author

Lei Zhu

Nanyang Technological UniversityORCID 0000-0003-1618-7570Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lei Zhu1 paper · McGill University

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:plant (other)· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

Zbynek BozdechiD· 2 shared Abul Faiz· 1 shared Arjen M. DondorpiD· 1 shared Aung Pyae PhyoiD· 1 shared Camilla Valente PiresiD· 1 shared Chanaki Amaratunga· 1 shared Chang LiiD· 1 shared Changqing ZhangiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersSystems Biology

Zbynek BozdechORCID

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3 papers

Recent·Most cited

BioinformaticsGenome biologyPeer-reviewedOct 16, 2023

MalariaSED: a deep learning framework to decipher the regulatory contributions of noncoding variants in malaria parasites

Chengqi C. Q. Wang, Yibo Dong, Chang Li…·Xiaoming Liu

MalariaSED predicts chromatin profiles in malaria parasites and identifies noncoding variants linked to invasion and drug resistance.

6 citations

ChIP-seqdeep learning

𝕏 PostBluesky

Systems BiologybioRxivPreprintMay 17, 2021

The mechanism of artemisinin resistance of Plasmodium falciparum malaria parasites originates in their initial transcriptional response.

Lei Zhu, Rob W. van der Pluijm, Michal Kucharski…·Zbynek Bozdech

The paper identifies a transcriptional profile in artemisinin-resistant Plasmodium falciparum that originates from initial drug responses and involves proteotoxic stress and REDOX metabolism.

1 citation

plant (other)bulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintFeb 12, 2020

Antagonistic roles of NOT1 paralogues in the timing of gene expression in Plasmodium falciparum

Ying Liu, Ragini Rai, Lei Zhu…·Zbynek Bozdech

This study shows that two NOT1 paralogues in Plasmodium falciparum have opposing roles in regulating mRNA abundance during the intraerythrocytic developmental cycle.

1 citation

plant (other)bulk RNA-seq

𝕏 PostBluesky