Author

Gregory Gauthier-Coles

Australian National UniversityORCID 0000-0002-4725-5313Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Angelika Bröer· 2 shared Stefan BröeriD· 2 shared Abhijit DasiD· 1 shared Alice Shaam Al AbediD· 1 shared Alison Marie TayloriD· 1 shared Angela L. NicoliiD· 1 shared Brian BillupsiD· 1 shared Caroline D. RaeiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersNeuroscience

Angelika Bröer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Systematic analysis of genetic vulnerabilities caused by chromosome loss events in cancer

Yi Bei, Jessica Keane, Mason Lynch, Kurt M. Tamaru, Suyeon Lee, Lu Qiao, Pranav K. Kandikuppa, Gregory Gauthier-Coles, Wenqi Zhao, Klaske M. Schukken, Ines Forrest, Sarah L. Thompson, Stephanie K. Roessler, Alison Marie Taylor, Jason M. Sheltzer

This study identifies genetic vulnerabilities from chromosome loss events in cancer by analyzing CRISPR screening data and copy number profiles, revealing paralogous gene dependencies as therapeutic targets.

bioRxiv · Oct 28, 2026 · PreprintCancer Biology

Glutamine Transport via Neurotransmitter Transporter 4 (NTT4, SLC6A17) Maintains Presynaptic Glutamate Supply at Excitatory Synapses in the Central Nervous System

Angela L. Nicoli, Alice Shaam Al Abed, Sarah R. Hulme, Abhijit Das, Gregory Gauthier-Coles, Angelika Bröer, Sarojini Balkrishna, Gaétan Burgio, Nathalie Dehorter, Caroline D. Rae, Stefan Bröer, Brian Billups

This study identifies NTT4/SLC6A17 as a presynaptic glutamine transporter essential for glutamate supply and neurotransmission, with behavioral implications.

bioRxiv · Oct 20, 2024 · PreprintNeuroscience

A unified model of amino acid homeostasis in mammalian cells

Gregory Gauthier-Coles, Jade Vennitti, Zhiduo Zhang, William C. Comb, Kiran Javed, Angelika Bröer, Stefan Bröer

The paper develops a computational model to simulate amino acid translocation and demonstrates its ability to predict cytosolic concentrations in cancer cell lines and myotubes.

bioRxiv · Feb 8, 2021 · PreprintSystems Biology