Author

Pauline Trébulle

Centre for Human GeneticsORCID 0000-0002-4729-5032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Approach:statistical model· 3 Organism:yeast· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Markus RalseriD· 3 shared Michael MüllederiD· 3 shared Fatma Amari· 2 shared Joseph SchachereriD· 2 shared Julia MuenzneriD· 2 shared Andrea D. LehmanniD· 1 shared Anna-Sophia EggeriD· 1 shared Anne FriedrichiD· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersSystems Biology

Markus RalserORCID

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3 papers

Recent·Most cited

A genome-to-proteome atlas charts natural variants controlling proteome diversity and forecasts their fitness effects

Christopher M. Jakobson, Johannes Hartl, Pauline Trébulle, Michael Mülleder, Daniel F. Jarosz, Markus Ralser

The paper links genome to proteome in yeast progeny to identify variants controlling proteome diversity and predict their fitness effects under stress.

bioRxiv · Oct 18, 2024 · PreprintSystems Biology

The natural diversity of the yeast proteome reveals chromosome-wide dosage compensation in aneuploids

Julia Muenzner, Pauline Trébulle, Federica Agostini, Henrik Zauber, Christoph B. Messner, Martin Steger, Christiane Kilian, Kate Lau, Natalie Barthel, Andrea D. Lehmann, Kathrin Textoris‐Taube, Élodie Caudal, Anna-Sophia Egger, Fatma Amari, Matteo De Chiara, , Markus Ralser

The paper quantifies proteomic effects of aneuploidy in natural yeast isolates, finding chromosome-wide dosage compensation in the proteome but not transcriptome.

Nature · May 22, 2024Peer-reviewedSystems Biology

Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast

Élie Teyssonnière, Pauline Trébulle, Julia Muenzner, Victor Loegler, Daniela Ludwig, Fatma Amari, Michael Mülleder, Anne Friedrich, Jing Hou, Markus Ralser, Joseph Schacherer

The paper quantifies transcriptomes and proteomes across 942 yeast isolates, showing weak correlation between mRNA and protein levels and distinct genetic control mechanisms.

Proceedings of the National Academy of Sciences · May 2, 2024Peer-reviewedSystems Biology