Nicolas Vitale

Endoplasmic reticulum membrane contact sites coordinate exocytic site assembly and activity in neuroendocrine cells

This study identifies ER membrane contact sites (MCS) as regulators of exocytic site assembly and activity in neuroendocrine cells by coordinating calcium signaling and actin dynamics.

Chromogranin A regulates the dynamics of neurosecretion through its interaction with phosphatidic acid

This study identifies a direct interaction between chromogranin A and phosphatidic acid at the plasma membrane, showing how this interaction regulates neurosecretion dynamics.

Dual-action peptide shuttles rescue Cu-amyloid-beta-induced neurotoxicity and relocate Cu intracellularly

The paper designs and tests Cu(II)-selective peptide shuttles that reduce Cu-Aβ-induced neurotoxicity and redistribute Cu intracellularly.

Designing new natural-mimetic phosphatidic acid: aversatile and innovative synthetic strategy forglycerophospholipid research

This paper introduces a new synthetic strategy for phosphatidic acid analogues that preserves acyl chain structure and enables flexible molecular grafting for biological studies.

Ral GTPases promote metastasis by controlling biogenesis and organ colonization of exosomes

This study shows Ral GTPases regulate exosome biogenesis and organ colonization, promoting metastasis through MCAM/CD146 modulation in breast cancer.