Carlos Escande

This study shows nitazoxanide activates BMP9-ALK1-SMAD signaling and reduces HHT vascular abnormalities by modulating mTOR activity in endothelial cells.

This study shows that deleting Dbc1 in adipocytes does not cause healthy obesity but reveals a role for Dbc1 in inflammation during obesity.

This study identifies ERK1/2 phosphorylation as a mediator of FSTL1's role in ciliogenesis and preadipocyte differentiation, showing FSTL1 antagonizes BMP non-canonical signaling.

This paper generates Ccdc28b mutant mice and finds they exhibit social behavioral defects and autism-like features, suggesting a link between CCDC28B and autism spectrum disorder beyond its role as a modifier of Bardet-Biedl syndrome.