Hamid Rabb

STcompare identifies differentially spatially patterned genes by comparing spatial correlation and fold-change across structurally matched tissues in spatial transcriptomics data.

The paper uses spatial transcriptomics to analyze cold ischemia injury in murine kidneys, identifying compartment-specific metabolic changes and providing an interactive browser for results.

This study shows that gut microbes regulate glomerular filtration rate (GFR) in mice, with their suppression increasing GFR in both healthy and chronic kidney disease models.

This study shows that inhibiting MTAP reduces kidney injury markers and improves renal histology in AKI mouse models and links MTAP expression to kidney injury in human single-cell RNA sequencing data.