BioengineeringBioengineering & Translational MedicinePeer-reviewed
Harnessing micrometer-scale tPA beads for high plasmin flux and accelerated fibrinolysis
Matthew J. Osmond, Fabrice Dabertrand, Nidia Quillinan…·Keith B. Neeves
This paper develops micrometer-scale tPA beads that enhance plasmin generation and fibrinolysis, achieving rapid thrombus removal in a mouse stroke model with lower doses than standard tPA.
4 citations