Author

Alejandro Miguel Katzin

Universidade de São PauloORCID 0000-0002-4782-2162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Gabriela Oliveira CastroiD· 2 shared Ignasi Bofill VerdagueriD· 2 shared Manoel Aparecido Peres· 2 shared Marcell CrispimiD· 2 shared Maurício Mazzine Filho· 2 shared Agustín HernándeziD· 1 shared Arthur Vicentini Furtado· 1 shared Carlos Alberto de Araújo Silva· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMicrobiology

Gabriela Oliveira CastroORCID

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2 papers

Recent·Most cited

Antimalarial Potential of Synthetic Geraniol and Nerol Analogs

Maurício Mazzine Filho, Isaac Agnelo da Silva Sobreiro, Gabriel dos Santos e Silva, Carlos Alberto de Araújo Silva, Leonardo Vinícius Nogueira Lima, Arthur Vicentini Furtado, João Vitor da Silveira, M.V.N. De Souza, Matheus Felipe Silva Santos, Gabriela Oliveira Castro, Manoel Aparecido Peres, Marcell Crispim, Alejandro Miguel Katzin, Maurício Frota Saraiva, Ignasi Bofill Verdaguer

This study identifies new acyclic monoterpene analogs with potent antiplasmodial activity and selectivity against P. falciparum in vitro, supported by favorable pharmacological properties.

Journal of Chemistry · Jan 1, 2026Peer-reviewedMicrobiology

4-Nitrobenzoate inhibits 4-hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim

This study shows that 4-nitrobenzoate inhibits 4-HPT in malaria parasites, enhances atovaquone efficacy in vitro and in vivo, and identifies chemical requirements for this potentiation.

FEBS Letters · Oct 14, 2025Peer-reviewedMicrobiology