Author

Gabriela Oliveira Castro

Universidade de São PauloORCID 0009-0008-8371-598XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alejandro Miguel KatziniD· 2 shared Ignasi Bofill VerdagueriD· 2 shared Manoel Aparecido Peres· 2 shared Marcell CrispimiD· 2 shared Maurício Mazzine Filho· 2 shared Agustín HernándeziD· 1 shared Arthur Vicentini Furtado· 1 shared Carlos Alberto de Araújo Silva· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMicrobiology

Alejandro Miguel KatzinORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of ChemistryPeer-reviewedJan 1, 2026

Antimalarial Potential of Synthetic Geraniol and Nerol Analogs

Maurício Mazzine Filho, Isaac Agnelo da Silva Sobreiro, Gabriel dos Santos e Silva…·Ignasi Bofill Verdaguer

This study identifies new acyclic monoterpene analogs with potent antiplasmodial activity and selectivity against P. falciparum in vitro, supported by favorable pharmacological properties.

DOI 10.1155/joch/8576949

biophysical modelingdrug response / drug discovery

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MicrobiologyFEBS LettersPeer-reviewedOct 14, 2025

4-Nitrobenzoate inhibits 4-hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho…·Marcell Crispim

This study shows that 4-nitrobenzoate inhibits 4-HPT in malaria parasites, enhances atovaquone efficacy in vitro and in vivo, and identifies chemical requirements for this potentiation.

DOI 10.1002/1873-3468.70186

humanmouse

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