Marcell Crispim

This study identifies new acyclic monoterpene analogs with potent antiplasmodial activity and selectivity against P. falciparum in vitro, supported by favorable pharmacological properties.

This study shows that 4-nitrobenzoate inhibits 4-HPT in malaria parasites, enhances atovaquone efficacy in vitro and in vivo, and identifies chemical requirements for this potentiation.

This study shows that disrupting the hexosamine biosynthetic pathway in Plasmodium falciparum blocks GPI production, arrests parasite growth, and prevents egress from host cells.

This study investigates the transport and metabolic roles of serine, threonine, and glycine in Trypanosoma cruzi, showing their importance in energy metabolism and stress response.