Frontal noradrenergic and cholinergic transients exhibit distinct spatiotemporal dynamics during competitive decision-making
Hongli Wang, Heather K. Ortega, Emma B. Kelly, Jonathan Indajang, Neil K. Savalia, Samira Glaeser-Khan, Jiesi Feng, Yulong Li, Alfred P. Kaye, Alex C. Kwan
This study uses two-photon microscopy to show that NE and ACh transients have distinct spatiotemporal dynamics during decision-making in mice, with NE promoting exploration.
Science Advances · Mar 26, 2025Peer-reviewedNeuroscience