Abdalla D. Mohamed

This study identifies lipid senolytics that kill senescent cells via ferroptosis, extending healthspan in mice by targeting ACSL4, LPCAT3, and ALOX15.

This study identifies fucoidans as senotherapeutics that enhance SIRT6-dependent DNA repair and reduce senescence in aged mice.

This study develops two novel flavonoid senolytics through phenotypic drug screening and design, showing enhanced senolytic activity and healthspan extension in a mouse model.

This study shows that muscle hypertrophy involves cancer-like metabolic reprogramming, with PHGDH playing a key role in regulating myotube size through glycolytic pathways.