Frank Lyko

This study maps the m6A landscape in bladder cancer, identifying global methylation dilution and 3'-UTR hypermethylation as key features.

This study identifies m6A RNA methylation as an antiviral mechanism in mosquito cells by regulating serine proteases that influence Zika virus replication.

This study evaluates improvements in direct RNA sequencing (DRS) using RNA004 chemistry and modified-base-calling models, showing enhanced throughput, accuracy, and detection of RNA modifications in clinical applications.

This study shows that m5C RNA modification in C. elegans affects translation efficiency and adaptation to heat stress by modulating leucine and proline decoding.

The paper develops a computational method to accurately call methylation in whole-transcriptome bisulfite sequencing data, revealing new methylation patterns in mouse RNAs.

This study shows that marbled crayfish, a parthenogenetic triploid, originated from P. fallax through autopolyploidy and is now an independent asexual species with distinct traits.