David Jordan

The paper shows that cells can detect chemotactic gradients with a minimal differential receptor activation of 0.026%, challenging the traditional ΔC framework.

The paper identifies a compensatory tRNA modification pathway mediated by DUS3L that allows oesophageal cancer cells to resist METTL1 loss, suggesting DUS3L as a biomarker and therapeutic target.

The paper identifies mutations in E3 ubiquitin ligases that restore development in SWI/SNF mutants in C. elegans, suggesting potential therapeutic targets for human developmental disorders.

This study shows that m5C RNA modification in C. elegans affects translation efficiency and adaptation to heat stress by modulating leucine and proline decoding.

This study identifies a genetic pathway in C. elegans that regulates growth and phenotypic plasticity through environmental dsRNA uptake via SID-2.

The paper identifies and functionally characterizes long non-coding RNAs in C. elegans using transcriptome analysis and CRISPR/Cas9 mutagenesis.