RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses
Marisa M. Brockmann, Marta Maglione, Claudia Gisela Willmes, Alexander Stumpf, Boris Bouazza‐Arostegui, Laura Moreno Velasquez, M. Katharina Grauel, Prateep Sanker Beed, Martin Lehmann, Niclas Gimber, Jan Schmoranzer, Stephan J. Sigrist, Christian Rosenmund, Dietmar Schmitz
This study shows RIM-BP2 has different roles in neurotransmitter release at hippocampal mossy fiber and pyramidal CA3-CA1 synapses, with RIM-BP2 promoting vesicle docking/priming at mossy fibers by recruiting Munc13-1.
eLife · Sep 19, 2019Peer-reviewedNeuroscience