Author

Zhenhua Sun

ORCID 0000-0002-4899-6084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Chijian ZuoiD· 2 shared Jiafeng ZhuiD· 2 shared Jiali YangiD· 2 shared Qiangbo Hou· 2 shared Chunxi LiuiD· 1 shared Daolei Li· 1 shared Jiaojiao SuniD· 1 shared Lixiang Wei· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Chijian ZuoORCID

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2 papers

Recent·Most cited

Clean-PIE: a novel strategy for efficiently constructing precise circRNA with thoroughly minimized immunogenicity to direct potent and durable protein expression

Zonghao Qiu, Qiangbo Hou, Yang Zhao, Jiafeng Zhu, Mengting Zhai, Daolei Li, Yi Li, Chunxi Liu, Na Li, Yifei Cao, Jiali Yang, Zhenhua Sun, Chijian Zuo

Clean-PIE generates high-purity, low-immunogenic circRNAs that enable durable protein expression in vitro and in vivo.

bioRxiv · Jun 20, 2022 · PreprintMolecular Biology

Circular mRNA encoded PROTAC (RiboPROTAC) as a new platform for the degradation of intracellular therapeutic targets

Jiali Yang, Jiaojiao Sun, Jiafeng Zhu, Yaran Du, Yiling Tan, Lixiang Wei, Yang Zhao, Qiangbo Hou, Yan Zhang, Zhenhua Sun, Chijian Zuo

This paper introduces RiboPROTAC, a new platform using circular mRNA to degrade intracellular proteins, demonstrating its effectiveness in degrading GFP and PCNA with functional and immunological effects.

bioRxiv · Apr 22, 2022 · PreprintMolecular Biology